Updated on 09-16-2006

  

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Xu, Chenwu, Ph.D

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Professor of Statistical Genetics

Division of Biometrics and Quantitative Genetics

College of Agricultural Sciences

Yangzhou University

Yangzhou, 225009, China

Tel: 0086-514-7979358

Fax: 0086-514-7996817

Email: qtls@yzu.edu.cn

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EDUCATION AND TRAINING

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•Postdoctoral Research Associate, Statistical genetics/genomics, University of California, Riverside, Jaunary 2002-October 2003. (With Prof. SZ Xu)

•Ph.D. July 1998. Quantitative Genetics, Nanjing Agricultural University, P. R. China

•M.S. July 1989. Biometrics and Quantitative Genetics, Jiangsu Agricultural University, P. R. China

•B.S. July 1986. Agronomy, Jiangsu Agricultural University, P. R. China

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CURRENT APPOINTMENTS

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•Professor of Statistical Genetics, Division of Biometrics and Quantitative Genetics, College of Agricultural Sciences, Yangzhou University, August 2001-present

•Director of Division of Biometrics and Quantitative Genetics, May 2004-present

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PREVIOUS APPOINTMENTS

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•Associate Professor of Statistical Genetics, Division of Biometrics and Quantitative Genetics, College of Agricultural Sciences, Yangzhou University, August 1997-July 2001

•Assistant Professor of Statistical Genetics, Division of Biometrics and Quantitative Genetics, College of Agricultural Sciences, Yangzhou University, December 1991-July 1997

•Postdoctoral Research Associate, Statistical genetics/genomics, University of California, Riverside, Jaunary 2002-October 2003. (With Prof. SZ Xu)

•Research Associate, Statistics and Genetics, Jiangsu Agricultural University, July 1989-November 1991

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CURRENT TEACHING

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•Biometrics and Experimental Design for undergraduate students, Yangzhou University, 1991-present

•Quantitative Genetics for graduates, Yangzhou University, 1997-present

•Statistical Genomics for graduates, Yangzhou University, 2003-present

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RESEARCH AREAS

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•Statistical methods of gene mapping for complex traits

•Bayesian Statistics and Markov chain Monte Carlo algorithms

•Bayesian model selection

•Statistical analysis of genetic data

•Bioinformatics

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RESEARCH GRANTS

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AS PRINCIPAL INVESTIGATOR

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2006-2010

The Research of The Early Detection of Elite Parents and Its Evaluation System, National Basic Research Program of China (973 Program), Ministry of Science and Technology of China

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2006-2008

Statistical Method for Mapping Genes Controlling Complex Traits, Program for New Century Excellent Talents in University, Ministry of Education of China

2006-2008

Statistical Method for Dissecting the Quantitative traits with Chromosome Segment Substitution Lines, Natural Science Foundation of Jiangsu Province, Commission of Science and Technology of Jiangsu Province

2003-2006

Mapping Quantitative Trait Loci for Threshold Traits, National Natural Science Foundation of China

2002-2005

Mapping Quantitative Trait Loci with Multiple Correlated Populations, National Natural Science Foundation of China

2000-2002

Statistical Method of Mapping Quantitative Trait Loci Underlying Endosperm Character in Cereals, National Natural Science Foundation of China

1999-2002

Study on the Inheritance of Quality Traits in Wheat Varieties for Special Purpose, Commission of Education of Jiangsu Province

1999-2001

Wheat Breeding for Massive Yield and High Quality, Science and Technology Commission of Yangzhou City

1994-1999

Genetic Expression for Quality Traits of Rice Grains in Indica-Japonica Hybrids, Commission of Education of Jiangsu Province

1993-1996

Mapping Quantitative Trait Loci Underlying Quality Traits of Rice Grains, Commission of Education of Jiangsu Province

AS INVESTIGATOR

2002-2005

Rice Genome Sequence-Based Cloning of Major QTL Underlying Quality Traits, 863 Program, Ministry of Science and Technology of China

1995-2000

Computer Software for Mapping Quantitative Trait Loci, Ministry of Agriculture of China

1997-1999

Comparison and Integration of Quantitative Trait Loci Map, National Natural Science Foundation of China

1995-1997

Joint Mapping of Quantitative Trait Loci for Multiple Related Quantitative Traits, National Natural Science Foundation of China

1991-1995

Genetic Models and Statistical Methods for Qualitative-Quantitative Traits, Ministry of Agriculture of China and Ministry of Education of China

1986-1990

Studies on the Inheritance of Quality Characters in Cereals, Ministry of Agriculture of China

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HONORS AND AWARDS

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2005

Candidate of Young and Middle-aged Leading Academic Personnel for New Century Talents Program, Ministry of Education of China

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2003

The Second Batch Candidate of The ¡°Qinglan¡± Training Project for Leading Academic Personnel, Commission of Education of Jiangsu Province

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2000

Excellent Teacher Prize, Yangzhou University

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2000

First Class Award of Teaching in The Course of Biometrics and Experimental Design, College of Agricultural Sciences, Yangzhou University

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1999

Second Class Award of Science and Technology Development (ranked third), Ministry of Education of China

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1999

Candidate of Award of The 6th Youth Science and Technology, Government of Jiangsu Province

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1999

Excellent Teacher Prize, Yangzhou University

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1998

Youth Scientist Award, Yangzhou Administration

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1997

Third Class Award of Teaching in The Course of Biometrics and Experimental Design, Yangzhou University

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1997

Excellent Thesis of Natural Science, Yangzhou Administration

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1996

Excellent Youth Teacher Prize, Yangzhou University

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1995

Excellent Thesis Prize, Chinese Agronomy Association

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1993

Excellent Teacher Prize, Jiangsu Agricultural University

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1989

Excellent Graduate, Jiangsu Agricultural University

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1986

Exemplary Student, Jiangsu Agricultural University

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PROFESSIONAL MEMBERSHIPS

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•Organizing committee member of the National Conference on Animal and Plant Quantitative Genetics in China, 2005-present

•Committee of the Jiangsu Genetics Society, 2006-present

•Member of the Genetics Society of China, 1997-present

•Member of the China Association of Agricultural Sciences, 1994-present

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PEER REVIEW ACTIVITIES

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•Referee for Journals: Heredity, Bioinformatics, Theoretical and Applied Genetics, Chinese Science Bulletin, Acta Genetica Sinica, Hereditas, Scientia Agricultura Sinica, Acta Agronomica Sinica, Agricultural Sciences in China

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MANUSCRIPTS UNDER REVIEW

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1.    Xu CW, Wang XF, Li ZK, Xu SZ. 2006. A multivariate Bayesian approach to mapping quantitative trait loci. Genetics. (Submitted)

2.    Xiao J, Wang XF, Hu ZQ, Tang ZX, Xu CW. 2006. Multivariate segregation analysis for quantitative traits in line crosses. Heredity. (Revision)

3.    Wang XF, Hu ZQ, Wang W, Li YL, Zhang YM, Xu CW. 2006. A mixture model approach to the mapping of QTL controlling endosperm traits with bulked sample. Genetica. (Revision)

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SELECTED PUBLICATIONS

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PAPERS IN ENGLISH

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1.    Xiao J, Wang X, Hu Z, Tang Z, Xu C. Multivariate segregation analysis for quantitative traits in line crosses. Heredity  (2007) 98, 427¨C435 [pdf]

2.    Hu ZQ, Wang XF, Xu CW. A Method for identification of the expression mode and mapping of QTL underlying embryo-specific characters. Journal of Heredity. 2006, doi:10.1093/jhered/esl028

3.    He Y, Han YP, Jiang L, Xu CW, Lu JF, Xu ML. Functional analysis of starch-synthesis genes in determining rice eating and cooking qualities. Molecular Breeding, 2006 (In press)

4.    Xu SZ and Xu CW. A multivariate model for ordinal trait analysis. Heredity, 2006, doi:10.1038/sj.hdy.6800885

5.    Xiao J, Wang XF, Hu ZQ, Tang ZX, Sui J, Li X, Xu CW. Joint analysis method for major genes controlling multiple correlated quantitative traits. Agricultural Sciences in China, 2006, 5(3):179-187

6.    Hu ZQ, Xu CW. A new statistical method for mapping QTLs underlying endosperm traits. Chinese Science Bulletin, 2005, 50(14): 1470-1476

7.    Xu CW, Li ZK, Xu SZ. Joint mapping of quantitative trait loci for multiple binary characters. Genetics, 2005, 169: 1045-1059

8.    Xu CW, Zhang YM, Xu SZ. An EM algorithm for mapping quantitative resistance loci. Heredity, 2005, 94: 119-128

9.    Xu CW, Xu SZ. Mapping quantitative trait loci underlying triploid endosperm traits in cereals. Heredity, 2003, 90(3): 228-235

10.  Xu CW, Li T, Sun CS, Gu SL. Mapping quantitative trait loci controlling endosperm traits with molecular marker. Life Science Research, 2001, 5(4): 314-320

11.  Huang ZL, Tan XL, Xu CW, Vanavichit. A. Molecular mapping QTLs for gel consistency in rice. Chinese Agricultural Science, 2001, 33(6): 1-3

12.  Xu CW, He XH, Kuai JM. Mapping quantitative trait loci underlying endosperm traits in cereals with molecular markers, Agricultural Sciences in China, 2002, (1): 5-10

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PAPERS IN CHINESE WITH ENGLISH ABSTRACT

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1.    Ao Y, Xu CW. The QTL mapping method for eight-way crosses design. Acta Agronomica Sinica. 2006 (In press)

2.    Tang ZX, Wu WW, Xu CW. EM algorithm-based method for the estimation of recombination fraction. Journal of Biomathematics. 2006 (In press)

3.    Tang ZX, Wang XF, Wu WW, Xu CW. Bayesian statistics-based method for genetic linkage analysis. Hereditas. 2006, 28 (9): 1117-1122

4.    Tang ZX, Chen ZJ, Wang XF, Xu CW. Multi-point joint inference of QTL genotype in marker-assisted selection. Molecular Plant Breeding, 2006, 4 (2): 293-298

5.    Ao Y, Xu CW. Maximum likelihood method for mapping QTL in four-way crosses design. Acta Agronomica Sinica, 2006, 32(1): 51-56

6.    Chen HQ, Sun CS, Ding YH, Wang W, Li Tao, Gu SL, Xu CW. Quantitative genetic analysis of SDS sedimentary value and gluten content in wheat hybrids. Journal of Yangzhou University (Agricultural and Life Science Edition), 2005, 26(3): 58-61

7.    Ao Y, Xu CW. Bayesian method of linear regress ion analysis and its application in QTL mapping. Journal of Yangzhou University (Agricultural and Life Science Edition), 2005, 26 (2): 44-49

8.    Xiao J, Hu ZQ, Tang ZX, Sui JM, Li X, Xu CW. Joint analysis method for major genes controlling multiple correlated quantitative traits. Scientia Agricultura Sinica, 2005, 38 (9): 1717-1724

9.    Xu CW , Wang W , Hu ZQ , Sun CS. Plant average-based maximum likelihood mapping of quantitative traits loci controlling endosperm traits. Acta Agronomica Sinica, 2005, 31 (10): 1271-1276

10.  Hu ZQ, Xu CW. A new statistical method for mapping QTLs underlying endosperm traits. Chinese Science Bulletin, 2005, 50(14): 1480-1485

11.  Xu CW, Hu ZQ, Wang XF, Wang W. Segregation analysis method for detecting major gene controlling endosperm traits. Scientia Agricultura Sinica, 2005, 38 (7): 1317-1323

12.  Wang W, Hu ZQ, Sun CS, Xu CW. Single grain observation-based mapping of quantitative traits loci underlying endosperm traits. Acta Agronomica Sinica, 2005, 31 (8): 989-994

13.  Sun CS, Wang W, Li T, Xu CW. Quantitative genetic analysis for RVA characteristics of wheat flour. Journal of Triticeae Crops, 2005, 25 (2): 1-4

14.  He XH, Hu ZQ, Wang W, Xu CW. Statistical method for mapping QTL method controlling endosperm traits in cereals. Journal of Yangzhou University (Agricultural and Life Science Edition), 2005, 26(1): 45-50

15.  Tang ZX, Gao QS, Xu CW. Nonlinear equation fitting by Microsoft Office Excel and its application. Chinese Agricultural Science Bulletin, 2005, 21(3): 306-310 (In Chinese with English Abstract)

16.  Feng GN, Li DX, Zhou JM, He Y, Xu CW, Xu ML. QTL Mapping and epistasis analysis of yield associated traits in an DH population from indica-japonica cross of rice (Oryza sativa L.). Journal of Yangzhou University (Agricultural and Life Science Edition), 2004, 25(2): 5-10

17.  Yang ZF, Zhang F, Gu SL, Li T, Xu CW. The Development of identification for the genes of pre-harvest sprouting of wheat using comparative molecular genetics. Chinese Agricultural Science Bulletin, 2004, 20(5): 50-54

18.  Ao Y, Xu CW, Mo HD. Heterosis for quality traits of paddy grain in indica hybrids. Acta Agronomica Sinica, 2004, 30(8): 774-779

19.  Li T, Xu CW, Ding YH, Hu ZQ, Sun CS, Gu SL. Preliminary analysis of important phenotype traits of some wheat varieties (Lines). Journal of Yangzhou University (Agricultural and Life Science Edition), 2003, 24(2): 40-43, 48

20.  Li T, Xu CW, Hu ZQ, Li YL, Sun CS, Gu SL. RVA Pasting properties of wheat hybrid and the relations with their parents. Journal of Triticeae Crops, 2003, 23(1): 17-20

21.  Gu SL, Xu CW, Kuai JM, Zhang F. Applying improved C-E algorithm to solve constrained NLP. Journal of Yangzhou University (Agricultural and Life Science Edition), 2002, 23(3): 69-73

22.  Sun CS, Xu CW, He XH, Pan XB, Zou JH. Mapping quantitative trait loci with multiple environment experiment data. Journal of Yangzhou University (Agricultural and Life Science Edition), 2002, 23(2): 50-54

23.  Li T, Xu CW, Hu ZQ, Sun CS, Li Gang, Gu SL. Genetic potentials of wheat flour RVA pasting characteristics and cluster analysis. Life Science Research, 2002, 6(4): 288-292

24.  Li T, Xu CW, Hu ZQ, Sun CS, Gu SL. Genetic research on some important wheat quality traits and selection of varieties for noodle purpose. Journal of Triticeae Crops, 2002, 22(3): 11-16

25.  Gu SL, Xu CW, Kuai JM. Testing of opimal fitting nonlinear equation with contraction expansion algorithm. Journal of Yangzhou University (Natural Science Edition), 2001, 4(3): 16-19

26.  Yan CJ, Xu CW, Yi CD, Liang GH, Zhu LH, Gu MH. Genetic analysis of gelatinization temperature in rice via microsatellite (SSR) markers. Acta Genetica Sinica, 2001, 28(11): 1006-1011

27.  Xu CW, He XH, Pan XB. Mapping quantitative trait loci with multiple environmental experiment data, Journal of Yangzhou University (Agricultural and Life Science Edition), 2002, 23(6): 50-54

28.  Xu CW, He XH, Kuai JM. Mapping quantitative trait loci underlying endosperm traits in cereals, Scientia Agricultura Sinica, 2001, 34(2): 117-122

29.  He XH, Xu CW, Kuai JM. Statistical methods for mapping quantitative trait loci, Hereditas, 2001, 23(5): 482-486

30.  He XH, Xu CW, Kuai JM. Principal influencing factors for mapping quantitative trait loci, Acta Agronomica Sinica, 2001, 27(4): 469-475

31.  Yang CJ, Xu CW, Gu MH. Mapping QTLs for gelitinization temperature in rice, Acta Genetica Sinica, 2001, 28(11): 1006-1011

32.  Ao Y, Xu CW, Mo HD. Quantitative analysis for inheritance of quality characters in indica hybrid rice, Acta Genetica Sinica, 2000, 27(8): 706-712

33.  Huang ZL, Tan XL, Xu CW. Molecular mapping QTLs for gel consistency in rice, Scientia Agricultura Sinica, 2000, 33(6): 1-5

34.  Xu CW, Mo HD, Ao Y. Maximum likelihood method for the qualitative-quantitative inheritance of endosperm traits and its application in the genetic analysis for amylose content in indica rice, Scientia Agricultura Sinica, 2000, 33(2):23-29

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BOOK OR PROCEEDINGS

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1.    Xu CW, Xu SZ. Extended sib-pair method for mapping QTL. In: Saxton, Arnold (eds), Genetic Analysis of Complex Traits Using SAS, 2004, 201-222, Cary, NC: SAS Institute Inc. (Book chapter)

2.    Xu CW, Xu SZ. A SAS/IML program for mapping QTL in line crosses. In: SUGI 28 Proceedings, 2003, Paper 235: 1-6, Cary, NC: SAS Institute Inc. (Chapter)

3.    Proceedings of the 1st National Conference on Animals and Plants Quantitative Genetics in China. May 2000, Genetics Society of China. (Editor-in-Chief)

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